Intractable focal epilepsy
نویسندگان
چکیده
منابع مشابه
Surgical treatment of intractable epilepsy associated with focal cortical dysplasia.
Focal cortical dysplasias (FCDs) are congenital malformations of cortical development that are a frequent cause of refractory epilepsy in both children and adults. With advances in structural and functional neuroimaging, these lesions are increasingly being identified as a cause of intractable epilepsy in patients undergoing surgical management for intractable epilepsy. Comprehensive histologic...
متن کاملMultimodal imaging in nonlesional medically intractable focal epilepsy.
Identification and localization of epileptogenic zone (EZ) is vital in patients with medically-intractable focal epilepsy, who may be candidates for potentially curative resective epilepsy surgery. Presence of a lesion on magnetic resonance imaging (MRI) influences both diagnostic classification and selection for surgery. However, the implications for MRI-negative cases are not well-defined for...
متن کاملPersistent uncrossed corticospinal connections in patients with intractable focal epilepsy.
Corticospinal connections may be bilateral at birth, but a predominantly unilateral and crossed pattern develops by the toddler years. Acquired injury can alter the normal development of laterality such that uncrossed corticospinal connections persist, particularly if the injury is early in life and involves the motor system. Whether other developmental insults, such as childhood epilepsy, affe...
متن کاملSurgical Treatment of Intractable Epilepsy Associated with Focal Cortical Dysplasia
Focal cortical dysplasias (FCDs), initially thought to be rare, are a common cause of drugrefractory epilepsy in both children and adults. Successful resection and subsequent characterization of FCDs was first described by Taylor et al. in 1971 from pathological specimens obtained in patients treated for intractable temporal lobe epilepsy (Tassi, et al.,2001; Becker, et al.,2002; Tassi, et al.,...
متن کاملDifficult-to-Localize Intractable Focal Epilepsy: An "In-Depth" Look.
Commentary Monitoring with intracranial electrodes is the gold standard for identification of seizure-onset zones and mapping of eloquent cortex in patients with intractable focal epilepsy. Electrode implantation is guided by hypotheses about localization of the epileptogenic zones that are based on assessment of seizure semiology, interictal and ictal scalp-EEG, functional and anatomic neuroim...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2001
ISSN: 0022-3050
DOI: 10.1136/jnnp.71.3.417